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. 2018 Nov 20;12:433. doi: 10.3389/fncel.2018.00433

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Copyright © 2018 Lively, Wong, Lam and Schlichter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neonatal (P1) microglia: Exemplary pro- and anti-inflammatory proteins. Rat microglia were harvested 24 h after treatment with IFNγ + TNFα (I+T) or IL-4. (Upper) Representative Western blots for the pro-inflammatory markers, iNOS, COX-2 and PYK2, and the anti-inflammatory marker, MRC1/CD206. (Lower) Individual values show fold-changes with respect to unstimulated (control) microglia and the mean ± SD is indicated. Differences from control microglia are shown as: ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001, and ^∗∗∗∗p < 0.0001.