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. 2018 Nov 15;12:835. doi: 10.3389/fnins.2018.00835

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Copyright © 2018 Liu, Xue, Liu, Liu, Diao, Wang, Pan and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of orexin-A on the motor activity impairments induced by MPTP intoxication in pole test (A,B) and open field test (C). T-turn time (A) and T-LA time (B) in pole test were recorded on day 2 and day 8 after the cease of MPTP treatment. (C) Total distance traveled in 10 min-duration open field test was recorded on day 1 and day 7 after the cease of MPTP treatment. Values were mean ± SEM, n = 12–14. ^∗P < 0.05, ^∗∗∗P < 0.001 vs. control; ^##P < 0.01, ^###P < 0.001 vs. MPTP; ^Δ P < 0.05, ^ΔΔ P < 0.01 vs. orexin-A + MPTP. SB: SB334867.