Table 5.
Overall tuberculosis and pneumonia incidence and hazard ratios in statin users vs. propensity score–matched statin nonusers.
| Statin | ||
|---|---|---|
| Variables | No (n = 1984) | Yes (n = 1984) |
| Tuberculosis | ||
| Person-years | 14,570 | 16,040 |
| Follow-up time (year), Mean ± SD | 7.34 ± 3.25 | 8.08 ± 2.75 |
| Event, n | 75 | 37 |
| Rate | 5.15 | 2.31 |
| cHR (95% CI) | 1 (Reference) | 0.38 (0.26, 0.57) *** |
| aHR (95% CI) a | 1 (Reference) | 0.37 (0.25, 0.56) *** |
| Pneumonia | ||
| Person-years | 14,308 | 15,924 |
| Follow-up time (year), Mean ± SD | 7.21 ± 3.32 | 8.03 ± 2.75 |
| Event, n | 150 | 86 |
| Rate | 10.5 | 5.40 |
| cHR (95% CI) | 1 (Reference) | 0.49 (0.38, 0.64) *** |
| aHR (95% CI) a | 1 (Reference) | 0.47 (0.36, 0.61) *** |
Incidence in per 1000 person-years. a Data adjusted for age, sex, urbanization level, monthly income, occupation, comorbidities (sleep disorders, diabetes, hypertension, hyperlipidemia, mental disorders, alcohol-related illness, chronic kidney disease, tobacco use, CAD, stroke, and acute respiratory failure), and use of medication (ICSs and OSs). Abbreviations: cHR, crude hazard ratio; aHR, adjusted hazard ratio; ICSs, inhaled corticosteroids; OSs, oral steroids. *** p < 0.001.