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. 2018 Nov 6;7(11):419. doi: 10.3390/jcm7110419

Figure 2.

Figure 2

MiRNA–mRNA interactive network in EGFR-mutant lung adenocarcinoma. (A) Network of 149 miRNA-mRNA interactions in EGFR-mutated lung adenocarcinoma; (B) Network of 63 statistically significant miRNA–mRNA interactions in EGFR-mutated lung adenocarcinoma (p < 0.01). Circles and squares represent miRNAs and mRNAs, respectively. Red indicates an upregulated miRNA or mRNA, whereas blue indicates a downregulated miRNA or mRNA. A line indicates an miRNA–mRNA interaction. The color intensity is proportional to the fold change (continuous) of EGFR-mutated/wild-type lung adenocarcinoma.