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. 2018 Nov 15;9:2650. doi: 10.3389/fimmu.2018.02650

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Copyright © 2018 Cui, Ardell, Podolnikova and Yakubenko.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The expression of M1 (iNOS) and M2 (Arg I) markers on IFN-γ (M1) and IL-4 (M2) stimulated macrophages using Real Time-PCR. Statistical analyses were performed using paired Student t-tests (n = 3 per group). Data are presented as mean ± SEM. **P < 0.01, compared to non-activated (n/act). (B) The expression of fibrin-binding integrins during M1 and M2 polarization. Open bars—non-activated; black bars M1-polarized, gray bars M2-polarized macrophages. Statistical analyses were performed using Student's paired t-tests (non-activated to activated) (n = 3 per group). Data are presented as mean ± SEM. *P < 0.05.