Table 1.
Comparison of demographic and clinical characteristics and laboratory findings on emergency department (ED) arrival between survival and non-survival necrotizing fasciitis (NF) patients.
| Characteristics | Survivors (n = 667) | Non-Survivors (n = 40) | p-Value |
|---|---|---|---|
| Age, years | 57.2 (35.7–69.8) * | 60.7 (39.3–82.6) * | 0.09 |
| SBP at triage, mmHg | 146.5 (124.6–189.9) * | 141.4 (104.6–198.5) * | 0.93 |
| DBP at triage, mmHg | 85.1 (55.6–101.7) * | 78.7 (44.1–99.5) * | 0.79 |
| SOFA score | 4 (0–6) * | 9 (5–23) * | <0.001 |
| Episodes of hypotension, n (%) | 86 (12.90%) # | 19 (47.50%) # | <0.01 |
| Hypothermia (BT < 36), n (%) | 78 (11.70%) # | 10 (25.0%) # | 0.56 |
| Hyperthermia (BT >= 38), n (%) | 150 (22.49%) # | 9 (22.50%) # | 0.94 |
| Acidosis, n (%) | 106 (16.04%) # | 10 (25.0%) # | <0.001 |
| Coagulopathy, n (%) | 95 (14.24%) # | 11 (27.5%) # | <0.001 |
| Thrombocytopenia, n (%) | 69 (10.34%) # | 7 (17.5%) # | 0.23 |
| Anemia, n (%) | 88 (13.19%) # | 11 (27.50%) # | 0.08 |
| Hypoxia, n (%) | 65 (9.75%) # | 6 (15.0%) # | 0.07 |
| Heart failure, n (%) | 163 (24.43%) # | 11 (27.5%) # | 0.24 |
| Diabetes mellitus, n (%) | 193 (28.94%) # | 14 (35.0%) # | 0.26 |
| Liver cirrhosis, n (%) | 141 (21.14%) # | 13 (32.5%) # | 0.15 |
| Chronic kidney disease, n (%) | 207 (31.03%) # | 14 (35.05%) # | 0.34 |
| Blood lactate (mmol/L) | 2.8 (0.5–5.6) * | 6.6 (1.2–11.8) * | <0.001 |
| Serum albumin (g/dL) | 3.1 (2.1–4.8) * | 2.6 (1.9–3.6) * | <0.001 |
| Serum creatinine (mg/dL) | 1.7 (0.5–3.8) * | 2.4 (0.9–6.6) * | <0.01 |
| Serum glucose (mg/dL) | 163 (121.5–188.9) * | 192 (128.6–246.5) * | <0.01 |
| CRP (mg/dL) | 124.1 (56.1–174.5) * | 161.7 (65.8–205.6) * | <0.01 |
* Values are median (interquartile range). # Numbers in parentheses denote percentages. BT, body temperature; CRP, C-reactive protein; DBP, diastolic blood pressure; SBP, systolic blood pressure; SOFA, sequential organ failure assessment.