Figure 3.

Pore size of hAQP7 monomer A at pH 5.0 and pH 7.0. Surface of a representative snapshot of monomer A (based on van der Waals radii): Red = smaller than single H₂O, green = single H₂O, blue = larger than single H₂O. Pore size represented as an average of all monomers in five simulations at each pH value (pH 5.0 in black and pH 7.0 in red traces). EP–extracellular pocket, ar/R–aromatic/arginine selectivity filter, NPA–NPA motif, CP–cytoplasmic pocket. Figure generated by HOLE [53] and VMD [63].