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. 2018 Nov 21;7(11):457. doi: 10.3390/jcm7110457

Table 1.

A summary of anatomy, scanning techniques, and clinical implications of the extremity cutaneous nerves.

Nerve Anatomy Scanning Technique Clinical Implication
Medial Brachial Cutaneous Nerve (MBCN) The MBCN travels at the posterior aspect of the axilla in proximity to the axillary vein. The transducer is placed on top of the teres major and latissimus dorsi muscles. The MBCN is located in the subcutaneous layer medial to the axillary neurovascular bundle. The MBCN can be injured during surgeries near the axillary fossa, such as lymph node dissection and breast augmentation.
Intercostobrachial Cutaneous Nerve (IBCN) The IBCN is the lateral cutaneous branch of the 2nd intercostal nerve. It pierces the intercostal and serratus anterior muscles, travels through the axilla, and reaches the middle aspect of the arm. The transducer is placed on top of the teres major and latissimus dorsi muscles. The IBCN can be seen in the subcutaneous layer on top of the teres major and latissimus dorsi muscles. The causes for injuries of the IBCN are similar to those of the MBCN.
Medial Antebrachial Cutaneous Nerve (MACN) The MACN pierces the brachial fascia, which overlies the biceps brachii muscle and courses at the ulnar aspect of the brachial artery. At the elbow level, the MACN runs together with the basilic vein. In the axillary fossa, the MACN can be seen on top of the axillary artery and vein, close to the median and ulnar nerves. The MACN can be identified distally following the basilic vein between the brachialis and the triceps brachii muscles. The most common causes of MACN injury are iatrogenic, e.g., venous punctures, injections for medial epicondylitis, or cubital tunnel releases.
Lateral Antebrachial Cutaneous Nerve (LACN) The LACN is the terminal sensory branch of the musculocutaneous nerve. The transducer is placed on the elbow crease. The short axis of the LACN can be seen lateral to the biceps tendon. The cephalic vein is located beside the LACN. Traumatic nerve injury during venipuncture is the main cause of LACN neuropathy. The second most common etiology is related to distal biceps tendon tears.
Posterior Antebrachial Cutaneous Nerve (PACN) The PACN is a branch of the radial nerve and departs from its main trunk near the outlet of the spiral groove, then it emerges to the subcutaneous level. The transducer is placed in the horizontal plane at the posterior mid-arm level. The radial nerve is seen underneath the lateral head of the triceps brachii muscle. Moving the transducer more distally, the PACN is seen leaving the radial nerve and then emerges at the subcutaneous level. The PACN might be entrapped by scar tissue or a neuroma may develop after a lateral epicondylitis surgery. In patients with recalcitrant lateral epicondylitis, ultrasound (US)-guided injection and/or radiofrequency ablation can be considered as alternative approaches for better pain relief.
Superficial Branch of the Radial Nerve (SBRN) After branching from the main trunk of the radial nerve, the SBRN descends underneath the brachioradialis muscle and lateral to the radial artery. The transducer is placed at the lateral side of the elbow crease to locate the radial nerve. Moving the transducer more distally, the SBRN is seen branching from the medial aspect of the radial nerve and descending underneath the brachioradialis muscle. A compressive neuropathy of the SBRN is also named Wartenberg’s syndrome. The causes of nerve entrapment include compression by a bracelet, watch, or handcuff and irritation from an adjacent metal implant. An SBRN neuropathy is also associated with de Quervain’s tenosynovitis.
Dorsal Cutaneous Branch of the Ulnar Nerve (DCBUN) The DCBUN branches from the ulnar nerve at the distal ulnar aspect of the forearm. It courses initially beneath the flexor carpi ulnaris tendon and pierces the deep fascia to reach the dorsal aspect of the wrist. The transducer is placed on the distal third of the ventral forearm to locate the flexor carpi ulnaris muscle, underneath which lies the ulnar nerve. Moving the transducer more distally, the DCBUN is seen branching from the medial aspect of the ulnar nerve. The risks of DCBUN neuropathy are similar to those of SBRN, e.g., compression by a bracelet or a metal plate fixed over the distal forearm. DCBUN neuropathy is associated with extensor carpi ulnaris tenosynovitis.
Palmar Cutaneous Branch of the Median Nerve (PCMN) The PCMN arises from the radial aspect of the median nerve at the distal forearm. It pierces the antebrachial fascia between the flexor carpi radialis and palmaris longus tendons. The transducer is placed on the distal forearm to visualize the median nerve. The PCMN emerges from the radial aspect of the median nerve. The PCMN later runs at the ulnar aspect of the flexor carpi radialis tendon. Since the PCMN is superficial to the flexor retinaculum, it can easily be damaged during carpal tunnel release. When a US-guided short-axis injection for carpal tunnel syndrome is performed from the radial aspect, the PCMN should again/first be located to prevent an accidental injury.
Anterior Femoral Cutaneous Nerve (AFCN) The AFCN is a branch of the femoral nerve. It divides into the intermediate and medial branches. The transducer is placed horizontally at the proximal thigh to locate the femoral neurovascular bundle. The femoral nerve can be visualized lateral to the femoral artery and vein. Moving the transducer more distally, the AFCN is seen departing from the femoral nerve and coursing above the sartorius muscle. An AFCN neuropathy commonly ensues due to iatrogenic injuries, e.g., a total knee replacement. Other causes comprise vein stripping, bypass grafting, lipoma excision, lymph node compression, and abscess removal.
Posterior Femoral Cutaneous Nerve (PFCN) The PFCN courses parallel and medial to the sciatic nerve. At the level of the inferior gluteal fold, the PFCN starts to surface and departs from the sciatic nerve. The transducer is placed on the proximal thigh, and the PFCN can be easily identified on the interval between the long head of the biceps femoris muscle and the semitendinosus muscle. The PFCN is in proximity to the origin of the hamstring muscle. The most common cause of PFCN neuropathy is due to a hamstring injury.
Lateral Femoral Cutaneous Nerve (LFCN) The LFCN usually passes underneath the inguinal ligament and runs in the fat compartment lateral to the sartorius muscle. The transducer is placed proximal and medial to the anterior superior iliac spine to visualize the LFCN on the iliacus muscle. The transducer is then relocated distally to see the LFCN course underneath the inguinal ligament. “Meralgia paresthetica” is a specific term used to describe symptoms regarding the entrapment of the LFCN. Common causes of nerve compression include tight clothing, increased belly fat, and pregnancy.
Sural Nerve The medial sural cutaneous nerve originates from the tibial nerve in the popliteal fossa, and the lateral sural cutaneous nerve branches from the common peroneal nerve. The lateral sural cutaneous nerve gives off the sural communicating branch and merges with the medial sural cutaneous nerve to become the sural nerve at the middle calf. Place the transducer at the mid-calf level to visualize the sural nerve on top of the gastrocnemius muscle. Moving the transducer distally, the sural nerve is visualized descending with the small saphenous vein and courses between the Achilles tendon and peroneus muscles at the distal leg. The sural nerve is in proximity to the small saphenous vein and can be injured during surgeries for varicose veins. Another cause of nerve injury would be related to Achilles tendon ruptures whereby the nerve may be entrapped by an adjacent hematoma
Saphenous Nerve The saphenous nerve is the terminal sensory branch of the femoral nerve and departs from the femoral nerve at the proximal thigh. It runs with the femoral artery inside the adductor tunnel and arises from the tunnel with the descending genicular artery. The transducer is placed in the horizontal plane at the proximal medial thigh to locate the adductor canal. The saphenous nerve can be seen inside the canal. Moving the transducer more distally, the saphenous nerve will be seen exiting the adductor canal together with the descending genicular artery. The saphenous nerve is vulnerable to injury during surgical interventions of the anterior medial knee. Common procedures that elicit a saphenous nerve injury include medial arthrotomy, meniscectomy, arthroscopic anterior cruciate ligament repair, and total knee replacement.