FIGURE 1.

MSCs package miR-133b into secreted exosomes. (A) Expression levels of miR-133b in injured spinal cords were measured by qRT-PCR at 12 h, 24 h, and at 2, 3, 4, 5, and 7 days after acute SCI. (B) Expressions of CD63, CD81, and CD9 in exosomes derived from miR-133b- or miR-con-transfected MSCs were evaluated by western blot. (C) Expression of miR-133b in exosomes derived from miR-133b- or miR-con-transfected MSCs was assessed by qRT-PCR. Values are presented as means ± SD. NS: p > 0.05, ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, n = 4 per group.