Table 1.
Patient characteristics
| Determinant | Investigated cohort (n = 521) | Bromcresol purple measured albumin (n = 331) | Bromcresol green measured albumin (n = 190) | p for difference |
|---|---|---|---|---|
| Demographic variables | ||||
| Age, years | 63.5 (14.1) | 63.3 (14.0) | 63.9 (14.5) | 0.62 |
| Gender, male | 323 (62) | 201 (61) | 122 (64) | 0.43 |
| BMI, kg/m2 | 24.8 (4.2) | 24.9 (4.5) | 24.8 (3.8) | 0.82 |
| Medical history | ||||
| SGA (normal, score 6–7) | 433 (83) | 268 (81) | 167 (88) | 0.01 |
| Diabetes | 102 (20) | 66 (20) | 36 (19) | 0.77 |
| Cardiovascular disease | 224 (43) | 140 (42) | 84 (44) | 0.67 |
| Residual kidney function* | 272 (52) | 162 (49) | 110 (58) | 0.05 |
| Dialysis parameters | ||||
| Dialysis vintage | 2.0 (1.0–3.8) | 2.0 (0.9–3.7) | 2.0 (1.2–4.0) | 0.33 |
| spKt/V | 1.37 (0.21) | 1.36 (0.20) | 1.38 (0.22) | 0.34 |
| Dialysis time, hours/week | 11.1 (1.4) | 11.1 (1.4) | 11.2 (1.5) | 0.40 |
| Laboratory values | ||||
| Hematocrit, L/L | 0.36 (0.04) | 0.36 (0.04) | 0.36 (0.04) | 0.77 |
| Cholesterol, mmol/L | 3.65 (0.98) | 3.59 (0.99) | 3.76 (0.95) | 0.06 |
| Creatinine, µmol/L | 876 (253) | 895 (239) | 844 (273) | 0.03 |
| Phosphate, mmol/L | 1.65 (0.50) | 1.70 (0.53) | 1.58 (0.44) | 0.01 |
| Albumin, g/L | 36.6 (4.7) | 34.5 (4.2) | 40.3 (3.1) | <0.0005 |
| Uncorrected calcium, mmol/L | 2.32 (0.18) | 2.32 (0.18) | 2.34 (0.17) | 0.26 |
| Corrected calcium#, mmol/L | 2.41 (0.19) | 2.45 (0.18) | 2.33 (0.18) | <0.0005 |
| Corrected calcium£, mmol/L | 2.28 (0.18) | 2.31 (0.18) | 2.22 (0.17) | <0.0005 |
| PTH, pmol/L | 29 (9–35) | 19 (9–36) | 20 (9–35) | 0.87 |
| Medication use | ||||
| Calcium-containing phosphate binders§ | 256 (49) | 170 (51) | 86 (45) | 0.19 |
| Calcium-free phosphate binders¶ | 361 (69) | 229 (69) | 132 (70) | 0.92 |
| Vitamin D analogue | 348 (67) | 213 (64) | 135 (71) | 0.11 |
| Statin | 272 (52) | 165 (50) | 107 (56) | 0.15 |
Data are shown are mean (SD), median (interquartile range) or number (percentage), when appropriate.
Conversion factors for units: haematocrit in L/L to %, (×100); cholesterol in mmol/L to mg/dL, (/0.02586), creatinine in µmol/L to mg/dL (/88.4); phosphate in mmol/L to mg/dL, (/0.3229); albumin in g/L to g/dL, (/10); calcium in mmol/L to mg/dL (/0.25); PTH in pmol/L to pg/mL (/0.106).
BMI, body mass index; SGA, subjective global assessment; PTH, parathyroid hormone.
*
Defined as diuresis >100 mL/24 h.
#
Albumin corrected calcium as calculated by the formula by Payne et al. [17].
£
Albumin corrected calcium as calculated by the formula by Orrell et al. [18].
§
Calcium carbonate and/or calcium acetate.
¶
Lanthanum and/or sevelamer.