Table 1.
Molecular weight profiles of the study formulas
| Molecular weight, Da | pHF E-akachan® | eHF MA-mi® | rCMF Hagukumi® |
|---|---|---|---|
| <500 | 54.1 | 65.2 | 46.7 |
| 500–1,000 | 21.0 | 22.6 | 14.6 |
| 1,000–1,200 | 7.5 | 6.7 | 4.9 |
| 1,200–2,000 | 9.2 | 4.4 | 7.4 |
| 2,000–3,500 | 5.4 | 1.1 | 5.5 |
| >3,500 | 2.9 | trace amountsa | 21.0 |
Defatted formula samples were applied to a high-performance liquid chromatography system (LC-20AD, Shimadzu, Tokyo, Japan) with a poly-hydroxyethyl aspartamide column (PolyLC, Columbia, MD, USA). pHF, partially hydrolyzed cow's milk formula; eHF, extensively hydrolyzed cow's milk formula; rCMF, regular cow's milk formula.
a
The hydrolysate for eHF was treated with ultrafiltration.