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Risdiplam tissue distribution in cynomolgus monkeys. Risdiplam concentration in plasma (ng/mL), CSF (ng/mL) and tissues (ng/g) of cynomolgus monkeys (n = 2) at Day 7 following once daily PO dosing (3 mg/kg/day for 7 days, Study 9). The blue and back bars represent the individual values for each of the two individual monkeys. CSF, cerebrospinal fluid; PO, per os
