TABLE 2.
Multivariate Analysis of Variables Associated With Progression of Acute Respiratory Compromise to Cardiopulmonary Arresta
| Variables | Adjusted Odds Ratio (95% CI) | p |
|---|---|---|
| Gender | ||
| Female | 1.38 (1.03–1.85) | 0.033 |
| Event location (compared with ICU) | ||
| Emergency department | 1.67 (1.13–2.48) | 0.011 |
| General inpatient area | 0.42 (0.26–0.69) | 0.005 |
| Respiratory status at the start of event | ||
| Apnea | 2.10 (1.23–3.58) | 0.007 |
| Agonal | 1.89 (1.06–3.39) | 0.032 |
| Assisted noninvasive ventilation | 1.81 (1.27–2.58) | 0.0010 |
| Rapid response team | ||
| No hospital-wide activation | 1.83 (1.03–3.22) | 0.038 |
| Intervention during event | ||
| Continuous positive airway pressure/bilevel positive airway pressure | 0.55 (0.33–0.93) | 0.026 |
| Reversal agent | 0.30 (0.11–0.85) | 0.023 |
| Sodium bicarbonate | 2.77 (1.73–4.34) | < 0.0001 |
| Central venous line | 2.58 (1.44–4.63) | 0.0015 |
| Failure of invasive airway placement on first attempt | 1.76 (1.20–2.59) | 0.0039 |
a
Multivariable analysis adjusted for age, race, illness category with generalized estimating equations to account for clustering within sites.