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Theoretical Rmax binding response of VEGF165.
| MW (kDa) |
RL
(RU) |
tRmax
(RU) |
Rmax from Equilibrium Fit (RU) |
Percent Active |
|
|---|---|---|---|---|---|
| VEGFR-1 Fc | 200 | 728.9 | 140 | 109 | 86 |
| VEGFR-2 Fc | 220 | 407.1 | 71.1 | 35 | 58 |
| NRP-1 Fc | 238 | 295.0 | 47.6 | 22 | 38 |
| NRP-1 mon | 94.5 | 166.3 | 67.6 | 31 | 41 |
Theoretical maximal responses were calculated using equation 1 and compared to maximal binding response observed on chips.
