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. 2018 Oct 25;7(11):bio038661. doi: 10.1242/bio.038661

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© 2018. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — Plag1 is required to regulate proliferation in the early embryonic telencephalon. (A–T) Analysis of the expression of BrdU (A–C), pHH3 (E–G), Pax6 (I–K), Tbr2 (M–O) and Tbr1 (Q–S) in E12.5 wild-type (A,E,I,M,Q), Plag1^KI/KI (B,F,J,N,R) and Plagl2^KI/KI (C,G,K,O,S) cortices. Quantification of the percentage of DAPI⁺ cells expressing BrdU (D), pHH3 (H), Pax6 (L), Tbr2 (P) and Tbr1 (T). Error bars are s.e.m. ns, not significant; *P<0.05, **P<0.01, and ***P<0.005. pp, preplate; vz, ventricular zone. Scale bars: 125 μm.