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Effect of drug combinations on biomarkers of apoptosis. Cells were exposed to the indicated drugs for 48 hrs and extracted proteins were analyzed by Western blotting (A and B). Genomic DNA was isolated from similar cells and analyzed by agarose gel electrophoresis with ethidium bromide staining (C). Results are representatives of two independent experiments. Bu, busulfan; 4HC, 4-hydroperoxycyclophosphamide; DAC, decitabine.
