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. 2018 Nov 22;9:2697. doi: 10.3389/fimmu.2018.02697

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Copyright © 2018 Jensen, Potts, Ready and Patterson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PROTAC-induced BRD peptides have sub-optimal affinity for BV173 alleles. Identified PROTAC-induced BRD peptides, mapped over predicted affinity of all potential BRD2 and BRD3 9-mers (IC50, nM) predicted with the SMM algorithm.