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. 2018 Nov 29;2018(11):CD012776. doi: 10.1002/14651858.CD012776.pub2

NCT03289663.

Trial name or title Effectiveness study of new generation bednets in the context of conventional insecticide resistance in the Democratic Republic of the Congo (Net‐PBO)
Methods Cluster‐randomized trial
Participants 1680 participants, 0‐10‐year‐old subjects in 30 villages
Interventions Control: bed net treated with pyrethroid only
Intervention: bed net treated with both pyrethroid and PBO
Outcomes Incidence rate of laboratory confirmed clinical cases of Malaria (time frame: participants will be actively followed up for 12 months and any suspected case of clinical malaria will immediately lead to microscopy and RDT for confirmation.) Microscopy to confirm the diagnosis of malaria sporozoite rate (time frame: Anopheles mosquitoes will be captured every 3 months during 1 year), sporozoite detection by ELISA to determine infectivity of Anopheles
Starting date 2 October 2017
Contact information  
Notes  

Abbreviations: ELISA: enzyme‐linked immunosorbent assay; PBO: piperonyl butoxide