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. 2018 Nov 29;51:54. doi: 10.1186/s40659-018-0204-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Tyrosinase gold labeling on melanocytes; Immunogold labeling electron microscopy showing the 10 nm diameter gold particles conjugated to tyrosinase molecules on melanocytes both in the cytoplasm (arrow in a, b and d, e) and melanosomes (c and f-1, low magnification, -2, higher magnification). The quantity of tyrosinase between sericin-treated (a–c) and non-treated (PEG) (d–f) groups was compared via the numbers of tyrosinase-positive fields in melanocytic cells as shown in bar graph (g)