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. 2018 Nov 28;15:31. doi: 10.1186/s12979-018-0136-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Expression of SOD2 in non-stimulated and stimulated CD56dim and CD56bright cells of the young, old and the oldest Data are presented as means ± SEM and show expression of the studied protein in NK cell subsets demonstrated as the percentage of cells with the expression of a particular protein (%) and mean fluorescence intensity (MFI). The same symbols over bars (^#, *^, ^) denote statistically significant differences between similarly treated CD56dim or CD56bright cells, i.e. respectively non-stimulated or stimulated by IL-2, LPS or PMA with ionomycin compared between: young vs. old (marked with ^#), young vs. oldest (marked with *) and old vs. oldest (marked with ^). 3 symbols denote p < 0.001; 2 symbols denote p < 0.01; 1 symbol denotes p < 0.05. Horizontal lines above paired bars denote statistically significant differences between respectively CD56dim or CD56bright cells non-stimulated vs. stimulated by IL-2, LPS or PMA with ionomycin within the same age group. a Expression of SOD2 in CD56dim cells (%). b Expression of SOD2 in CD56bright cells (%). c Expression of SOD2 in CD56dim cells (MFI). d Expression of SOD2 in CD56bright cells (MFI)