Table 1.

Comparison of the analyzed parameters between similarly treated CD56dim and CD56bright cells of the same age group

Parameter	Stimulation type	CD56dim vs. CD56bright
		young		old		oldest
		%	MFI	%	MFI	%	MFI
SIRT1	ns	** ↑ bright	–	*** ↑ dim	–	–	–
	IL2	–	** ↑ bright	–	–	–	–
	LPS	*** ↑ bright	–	* ↑ bright	–	–	–
	PMA/ion	–	*** ↑ bright	–	–	–	–
HSP70intr	ns	–	–	–	–	–	–
	IL2	* ↑ bright	** ↑ bright	–	–	–	–
	LPS	–	–	–	–	–	–
	PMA/ion	* ↑ bright	** ↑ bright	–	** ↑ bright	–	–
HSP70surf	ns	*** ↑ dim	*** ↑ dim	*** ↑ bright	*** ↑ dim	*** ↑ dim	*** ↑ dim
	IL2	–	–	*** ↑ dim	–	* ↑ dim	–
	LPS	*** ↑ bright	* ↑ dim	*** ↑ dim	–	*** ↑ dim	–
	PMA/ion	*** ↑ dim	*** ↑ dim	–	–	–	–
SOD2	ns	–	–	** ↑ dim	–	–	–
	IL2	–	–	–	* ↑ bright	*** ↑ bright	** ↑ bright
	LPS	–	–	–	–	** ↑ bright	–
	PMA/ion	–	–	–	–	–	–
TNF	ns	*** ↑ bright	*** ↑ dim	*** ↑ dim	*** ↑ dim	*** ↑bright	** ↑dim
	IL2	–	*** ↑ dim	–	*** ↑ dim	–	–
	LPS	*** ↑ dim	*** ↑ dim	*** ↑dim	*** ↑ dim	*** ↑ dim	** ↑ dim
	PMA/ion	*** ↑ dim	*** ↑ dim	*** ↑dim	*** ↑ dim	*** ↑ dim	** ↑ dim
IFN-γ	ns	–	–	*** ↑ dim	–	–	–
	IL2	–	–	–	–	–	–
	LPS	–	–	** ↑ dim	–	–	–
	PMA/ion	–	* ↑ dim	–	–	* ↑ bright	–

↑denotes significantly higher expression in dim or bright cells

'HSP70^intr' intracellular HSP70, 'HSP70^surf' surface HSP70, 'PMA/ion' PMA + ionomycin

*** p < 0.001; ** p < 0.01; * p < 0.05