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. 2019 Jan;14(1):172–178. doi: 10.4103/1673-5374.243722

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Copyright: © Neural Regeneration Research

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Main activated brain areas for empathy induced by images of pained facial expressions.

(A–D) The orange zones show that (A) the precentral gyrus (BA 44, −44, 12, 8), (B) the right insula (BA13, 56, −34, 22), (C) the right middle temporal gyrus (BA37, 42, −60, −2) and (D) the left cingulate gyrus (BA32, −4, 10, 40), which were activated under the stimulation of facial expressions of pain. The anterior cingulate cortex (BA32), anterior central gyrus (BA44), fusiform gyrus, and insula (BA13) were activated positively as major brain areas. BA: Brodmann area; (−44, 12, 8), (56, −34, 22), (42, −60, −2), (−4, 10, 40): Montreal Neurological Institute coordinate.