Table 3.
Relationship between FAM19A4 methylation and clinicopathological parameters in cervical cancer
| Parameters | Median Methylation | Methylation Rates | U | P* |
|---|---|---|---|---|
| Scores() | (%) | |||
| Age | ||||
| < 48 | 144.14(49.89–387.46) | 90.63(29/32) | 445.00 | 0.784 |
| ≥48 | 140.65(62.20–466.41) | 96.55(28/29) | ||
| Histology | ||||
| SCC | 145.37(62.54–450.44) | 94.44(51/54) | 144.00 | 0.321 |
| AC/ASC | 137.83(8.38–207.24) | 85.71(6/7) | ||
| Stage | ||||
| IA or IB1 | 153.17(67.84–387.46) | 91.67(33/36) | 409.00 | 0.548 |
| IB2 or above | 97.78(51.19–562.08) | 96.00(24/25) | ||
| Size | ||||
| ≤4 cm | 141.42(62.20–389.23) | 93.88(46/49) | 279.00 | 0.786 |
| > 4 cm | 123.54(23.42–807.25) | 91.67(11/12) | ||
| Lymph node metastasis | ||||
| yes | 167.28(77.43–604.86) | 100(10/10) | 227.00 | 0.585 |
| no | 140.65(55.49–366.61) | 92.16(47/51) | ||
SCC squamous cell carcinoma, AC adenocarcinoma, ASC adenosquamous carcinoma
*P>0.05,Mann-Whitney U Test, methylation scores were used to calculate the statistical difference