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Study design. Abbreviations: ABC, advanced breast cancer; CTX, C-terminal cross-linking telopeptide of type 1 collagen; d, day; HER2–, human epidermal growth factor receptor 2-negative; HR+, hormone receptor-positive; NSAI, non-steroidal aromatase inhibitor; P1NP, procollagen type 1 N-terminal peptide; PTH, parathyroid hormone.
