Table 1.

Cx46 Mutation Identified in Human Congenital Cataracts

Mutation	Location	Cataract Types	Inheritary	Family Origin	References
Human Cx46
D3Y	NT	Zonular Pulverulent	Autosomal dominant	Hispanic	[75]
L11S	NT	“Ant-egg”	Autosomal dominant	Danish	[74]
V28M	M1	Variable	Autosomal dominant (incomplete penetrance)	Indian	[71]
F32L	M1	Nuclear pulverulent & punutate	Autosomal dominant	Chinese	[67]
R33L	M1	Finely granular	Autosomal dominant	Indian	[77]
W45S	E1	Nuclear	Autosomal dominant	Chinese	[73]
P59L	E1	Nuclear punctuate	Autosomal dominant	Caucasian	[68]
N63S	E1	Zonular pulverulent	Autosomal dominant	British	[65]
R76G	E1/M2	Total	Autosomal dominant	Indian	[71]
R76H	E1/M2	Lamellar nuclear pulverulent	Autosomal dominant (incomplete penetrance)	Australian	[70]
T87M	M2	Pearl box	Autosomal dominant	Indian	[76]
P187L	E2	Zonular pulverulent	Autosomal dominant	Caucasian	[66]
N188T	E2	Nuclear pulverulent	Autosomal dominant	Chinese	[69]
S380Qfs	CT	Zonular pulverulent & punctuate	Autosomal dominant	British	[65]