Table 3.

Connexin Mutation Identified in Cataracts of Mouse and Rat

Mutation	Location	Cataract Types	Inheritary	Origin	References
Mouse Cx50
G22R	M1	Microphthalmia & dense cataract	Autosomal semidominant	Lop10 mutation cataract mouse	[91]
D47A	E1	Nuclear	Autosomal dominant	No2 cataract mouse	[89]
S50P	E1	Whole cataract & small eye	Autosomal dominant	ENU mutagenesis	[92]
V64A	E1/M2	Nuclear and zonular cataract & microphthalmia	Autosomal dominant	Mouse Aey5 generated by ENU mutagenesis	[90]
Rat Cx50
R340W	CT	Cataract	Autosomal semidominant	UPL rat strain	[93]
L7Q	NT	Cataract & microphthalmia	Autosomal semidominant		[95]
Rat Cx46
E42K	E1/M1	Nuclear	Autosomal recessive	Cataract rat strain	[94]