TABLE 3.
Associations of Pretransplant Melanoma With Outcomes After Organ Transplantation
Number of Events (%) | Person-years | Incidence Rate per 100,000 Person-years | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | |
---|---|---|---|---|---|
All-cause mortality | |||||
No pretransplant melanoma (n = 184,703) | 57,908 (31) | 1,156,958 | 5,005 | 1.0 | 1.0 |
Pretransplant melanoma (n = 336) | 107 (32) | 1,351 | 7,920 | 1.6 (1.3–1.9) | 1.3 (1.0–1.5) |
Melanoma-specific mortality | |||||
No pretransplant melanoma (n = 184,703) | 79 (0.04) | 1,156,958 | 6.8 | 1.0 | 1.0 |
Pretransplant melanoma (n = 336) | 6 (1.8) | 1,351 | 444 | 59 (26–136) | 27 (11–64) |
Incident posttransplant melanoma | |||||
No pretransplant melanoma (n = 184,703) | 787 (0.4) | 1,153,994 | 68 | 1.0 | 1.0 |
Pretransplant melanoma (n = 336) | 11 (3.3) | 1,330 | 827 | 10 (5.6–19) | 5.4 (2.9–9.8) |
Melanoma-specific death and incident melanoma models incorporate other death as a competing risk. Models are adjusted for sex, age at transplantation, non-Hispanic white versus other race/ethnicity, thoracic versus abdominal transplant, and year of transplantation.