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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Biochem Pharmacol. 2018 Aug 10;157:258–265. doi: 10.1016/j.bcp.2018.08.012

Table 1.

Demographic characteristics, diagnoses, prescribed treatment and toxicological analysis of individual cases of suicide victims with depressive disorders and their respective control subjects.

Case Gender1 Age2 PM3 Cause of death Treatment4 Drug blood levels5 Assay6
Case 1 F 35 39 Caustic intoxication TMT, SMZ negative FB, B, AC, IP
Control 1 F 33 43 Vehicle accident negative FB, B, AC, IP
Case 2 M 73 60 Gunshot wound ATD, BZD CIT FB, B, AC
Control 2 M 79 66 Vehicle accident negative FB, AC
Control 2b M 67 61 Cardiac arrest not performed B
Case 3 F 72 49 Jumping from height Untreated negative FB, B, AC, IP
Control 3 F 79 39 Vehicle accident negative FB, B, AC
Control 3b F 68 30 Breast Cancer Negative IP
Case 4 M 65 30 Drug intoxication ATD, BZD IMI, TIA, BZD, SUL, EtOH FB, B, AC, IP
Control 4 M 65 50 Vehicle accident negative B, AC, IP
Control 4b M 68 36 Breast Cancer negative FB
Case 5 F 58 27 Hanging ATD, BZD negative FB, B, AC, IP
Control 5 F 58 37 Vehicle accident BZD, PC negative FB, B, AC, IP
Case 6 M 42 19 Jumping from height ATD, APS CLO; BDZ, MET FB, B, AC, IP
Control 6 M 41 19 Laboral accident negative FB, B, AC, IP
Case 7 F 88 9 Jumping from height ATD, BZD positive: SER FB, B, AC, IP
Control 7 F 81 19 Cardiac arrest negative FB, B, AC, IP
Case 8 F 68 25 Jumping from height ATD SER FB, B, AC, IP
Control 8 F 68 38 Vehicle accident ASA negative FB, AC, IP
Control 8b F 73 8 Gastric cancer ASA not performed B
Case 9 F 64 27 Jumping from height ATD, BZD MIA; CIT IP
Control 9 F 66 16 Vehicle accident negative
Case 10 F 64 25 Jumping from height ATD, BZD CIT IP
Control 10 F 67 35 Cardiac arrest negative
Case 11 F 71 19 Jumping from height TEO, ASA negative IP
Control 11 F 70 18 Vehicle accident negative
Case 12 F 53 17 Jumping from height BZD BZD FB, B
Control 12 F 54 18 Lung cancer Negative B
Control 12b F 63 20 Cardiac arrest Negative FB
1

Gender, F: female; M: male.

2

Age at death (years).

3

PM: Postmortem delay (hours).

4

Treatment prescription coded at the time of death: antidepressants (ATD), benzodiazepines (BDZ), antipsychotics (APS), trimethoprim (TMT), sulfamethoxazole (SMZ), theophylline (TEO), acetylsalicylic acid (ASA) and piroxicam (PC).

5

Drugs, blood levels detected coded as: citalopram (CIT), imipramine (IMI), tiapride (TIA), benzodiazepines and metabolites (BDZ), sulpiride (SUL), ethanol (EtOH), clotiapine (CLO), metamizole (MET), sertraline (SER), mianserine (MIA).

6

Assay carried out in each case and matching control(s): FB: Agonist-stimulation of [35S]GTPγS binding; B: [3H]CP55,940 saturation binding assay; AC: agonist-inhibition of AC activity; IP: immunoprecipitation of [35S]GTPγS labeled Gα subunits.