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. Author manuscript; available in PMC: 2019 Jun 15.
Published in final edited form as: J Immunol. 2018 May 4;200(12):4059–4067. doi: 10.4049/jimmunol.1800207

FIGURE 5. Chronological aging correlated with lower production of neutrophils and basophils, and a shorter half-life of classical monocytes.

FIGURE 5

EDTA-treated blood samples from rhesus macaques were collected and stained (group 2; Table II) 1, 4, 7, 10, and 14 days after iv BrdU administration. The BrdU+ cell fraction, half-life, and daily production were measured and calculated respectively for neutrophils (A, D, H), basophils (B, E, G), and classical monocytes (C, F, I). Blood kinetics were expressed as the mean ± SD of the BrdU+ cell fraction for each age group. Nonparametric Spearman correlation tests were used to compare half-life and daily production of cell types against age of the animals. P < 0.05 was considered statistically significant.