Table 2.
6 months | 12 months | 36 months | 60 months | |||||
---|---|---|---|---|---|---|---|---|
DMbaseline (n = 46) |
preDMbaseline
(n = 52) |
DMbaseline
(n = 48) |
preDMbaseline
(n = 57) |
DMbaseline
(n = 46) |
preDMbaseline
(n = 55) |
DMbaseline
(n = 32) |
preDMbaseline
(n = 38) |
|
Weight (kg) | 98.5 (85, 105.7) | 95.8 (83.9, 103.3) | 84.3 (77, 100.5) | 83 (72.3, 94) | 82.8 (75.8, 99.3) | 84.8 (70.6, 93.8) | 85.3 (77, 105.8) | 77.1 (70.5, 91.9) |
BMI (kg/m2) | 38.3 (33.9, 40.7) | 37 (33.9, 41.3) | 33.7 (30.8, 38.4) | 32.6 (28.6, 37.7) | 32.5 (29.3, 37) | 33 (28.3, 37.4) | 34.5 (29.8, 39.4) | 32 (28.8, 36.7) |
Body fat (%) | 38.4 (32, 42.6) | 39.6 (33.4, 43.1) | 34.5 (27.2, 38.3) | 34.5 (26.9, 39.3) | 36.1 (25.4, 41.6) | 32.7 (24.6, 42) | 35.6 (32.4, 37.1) | 33.6 (28.5, 45.5) |
Waist (cm) | 116 (103, 126.3) | 111 (104, 122.5) | 108 (98, 117) | 104 (97.3, 112.5) | 105.5 (98.5, 116.3) | 104 (95, 113) | 103 (97.5, 120.3) | 102 (91, 111) |
Fasting plasma glucose (mg/dl) | 96 (85.8, 109.3) | 87 (79, 93) | 91 (80.8, 99.3) | 83 (79, 90) | 92 (82, 100.8) | 84.5 (80.3, 92.8) | 91.5 (86.8, 99.8) | 86 (80, 94) |
Plasma insulin (μU/ml) | 7 (4, 12) | 8 (5, 11.7) | 6 (4, 8.2) | 5 (3.9, 7.2) | 5 (3, 7.4) | 5.7 (4, 8) | 6 (4, 8) | 6 (4, 8) |
C-peptide (ng/ml) | 2.8 (2, 3.5) | 2.6 (2.2, 3.1) | 2 (1.6, 2.6) | 2 (1.7, 2.4) | 2 (1.4, 2.5) | 2 (1.5, 2.4) | 1.9 (1.5, 2.6) | 2 (1.5, 2.3) |
HOMA-IR | 1.8 (1.1, 3.3) | 1.6 (1.1, 2.4) | 1.4 (0.9, 1.9) | 1.1 (0.7, 1.6) | 1.1 (0.7, 1.7) | 1.1 (0.8, 1.8) | 1.4 (1, 1.9) | 1.2 (0.8, 1.8) |
HbA1c (%) | 5.3 (5.1, 5.6) | 5 (4.8, 5.4) | 5.3 (5, 5.6) | 5.2 (4.8, 5.3) | 5.4 (5.2, 5.7) | 5.1 (4.9, 5.4) | 5.7 (5.4, 5.9) | 5.3 (4.9, 5.6) |
Total Cholesterol (mg/dl) | 166 (145, 180) | 163 (143.5, 180.5) | 160.5 (144.8, 178.5) | 155 (137.3, 175.3) | 178 (158.3, 190) | 167.5 (142, 184.8) | 177 (162.8, 196) | 175 (146, 194) |
LDL-c (mg/dl) | 97 (81, 109) | 94 (84, 111) | 94 (75, 107.5) | 85 (71.8, 100.3) | 104.5 (84.3, 119) | 88.5 (71.3, 109.3) | 104 (89, 114.5) | 89 (76, 112) |
HDL-c (mg/dl) | 41 (36, 46) | 43 (38.5, 50.5) | 48 (42, 52.5) | 50.5 (43, 60) | 53 (44, 60) | 56 (48, 69.8) | 56 (49, 64) | 61 (51, 72) |
Triglycerides (mg/dl) | 117 (91, 157) | 102 (82, 127) | 93 (75, 124.5) | 82 (67, 108.3) | 93 (72.8, 119.3) | 86 (72.3, 118.8) | 97 (76, 116) | 89 (66, 108) |
SBP (mm Hg) | 130 (120, 150) | 126 (119, 138) | 123 (110, 136) | 120 (110, 137) | 130 (122, 140) | 120 (117, 130) | 131 (120, 140) | 130 (119, 144.5) |
DBP (mm Hg) | 72 (70, 81.8) | 71 (70, 80) | 72 (69.5, 77.5) | 70 (65, 79) | 75 (68.8, 78.5) | 70 (63, 78) | 76 (70, 81.3) | 70 (64.5, 79) |
Data are shown as median and quartiles. SBP systolic blood pressure, DBP Diastolic blood pressure, LDL-c LDL cholesterol, HDL-c HDL cholesterol