Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 26;13:7997–8012. doi: 10.2147/IJN.S183796

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

The cellular uptake of Cur-Sol and Cur-PMs in normal and LP Caco-2 cells.

Notes: Uptake of Cur-Sol and Cur-PMs at (A) different concentrations for 1 hour and (B) different incubation time with 20 µg/mL Cur (mean ± SD, n=3, *P<0.05 vs TP-PMs, **P<0.01 vs TP-PMs). (C) The inhibitory effects of Gly-Sar in the cellular uptake of Cur-PMs in LP Caco-2 cells (mean ± SD, n=3, **P<0.01 vs TP-PMs, and ^##P<0.01 vs Val-PMs or Phe-PMs). (D) The endocytosis pathways of Val-PMs by leptin-stimulating Caco-2 cells (mean ± SD, n=3, **P<0.01 vs control).

Abbreviations: Cur, curcumin; Cur-Sol, Cur solution; Glysar, glycylsarcosine; LP, leptin treated; Phe-PMs, Cur loaded phenylalanine – D-α-tocopheryl polyethylene glycol 1000 succinate micelles; PM, polymeric micelle; TP-PM, D-α-tocopheryl polyethylene glycol 1000 succinate micelle; Val-PMs, Cur loaded valine – D-α-tocopheryl polyethylene glycol 1000 succinate micelles.