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. 2010 Apr 27;15(5):3048–3078. doi: 10.3390/molecules15053048

Table 1.

HIV-1 IN inhibitory potency of the quinoline scaffold.

Compound 3’ProcessingIC50 (μM) Strand Transfer IC50 (μM) Reference
2b graphic file with name molecules-15-03048-i001.jpg >100.000 >100.000 14
3a graphic file with name molecules-15-03048-i002.jpg >100.000 >100.000 19
3b graphic file with name molecules-15-03048-i003.jpg >100.000 114.000 14
4 graphic file with name molecules-15-03048-i004.jpg 77.000 untested 19
7 graphic file with name molecules-15-03048-i005.jpg >100.000 untested 19
12 graphic file with name molecules-15-03048-i006.jpg >100.000 untested 21
10 graphic file with name molecules-15-03048-i007.jpg 47.000 untested 21
5 graphic file with name molecules-15-03048-i008.jpg >100.000 untested 20
13 graphic file with name molecules-15-03048-i009.jpg 0.033 23
14 graphic file with name molecules-15-03048-i010.jpg 0.370 22