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. 2010 Apr 27;15(5):3048–3078. doi: 10.3390/molecules15053048

Table 3.

HIV-1 IN inhibitory potency of various 7-substituted 8,3’,4’-trihydroxystyrylquinolines.

graphic file with name molecules-15-03048-i012.jpg 3’-Processing IC50 (μM) Strand Transfer IC50 (μM) Reference
34 X = CN 3.0 Untested 14
35 X = CO2H 2.4 1 14
54 X = CO2CH3 >100 >100 26
42 graphic file with name molecules-15-03048-i013.jpg 2a 30
43 graphic file with name molecules-15-03048-i014.jpg Untested 2.4 30
46 X = (HO)2PO Untested >100 30
47 X = HO2CCO 100 >100 32
53 graphic file with name molecules-15-03048-i015.jpg 2.3 Untested 14
56 graphic file with name molecules-15-03048-i016.jpg 100 Untested 30
55 graphic file with name molecules-15-03048-i017.jpg >300 Untested 19

a overall binding assay.