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. 2010 May 14;15(5):3517–3555. doi: 10.3390/molecules15053517

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© 2010 by the authors;

licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Caffeine and structurally related methylxanthines found primarily in tea (theophylline) and chocolate (theobromine); paraxanthine is the main hepatic metabolite of caffeine after coffee ingestion.