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. 2010 Apr 27;15(5):2949–2961. doi: 10.3390/molecules15052949

Table 3.

Suzuki-Miyaura reactions between monosubstituted products 6a or 6b and various arylboronic acids.

Entry Aryl 1 Aryl 2 Product Yield %
1 4-MeO-Ph- 4-Cl-Ph- 8 55
2 4-MeO-Ph- Ph- 9 64
3 4-MeO-Ph- 4-F-Ph- 10 43
4 4-MeO-Ph- 2-Tolyl- 11 50
5 4-MeO-Ph- 3-CF3-Ph- 12 57
6 4-Cl-Ph- 4-MeO-Ph- 13 54
7 4-Cl-Ph- Ph- 14 62
8 4-Cl-Ph- 4-F-Ph- 15 57
9 4-Cl-Ph- 2-Tolyl- 16 58

Reaction conditions: arylboronic acid (2 equiv.), Pd(PPh3)4 (2.5 mol %), Na2CO3 (3 equiv.), DMF/ethanol (9 : 1), MW 300 W, 150 °C, 3 h