Table 2.
Behavioral changes at different time points for mice among seven groups
| Number | Before injection | 7 d after injection | 10 d after injection | 12 d after injection | 14 d after injection | |
|---|---|---|---|---|---|---|
| Normal group | 10 | 8.06 ± 0.71 | 8.22 ± 0.80 | 8.17 ± 0.75 | 8.19 ± 0.86 | 8.63 ± 0.53 |
| PD group | 10 | 8.46 ± 0.36 | 6.55 ± 0.63* | 6.05 ± 0.35* | 6.51 ± 0.81* | 7.11 ± 0.68* |
| NC group | 10 | 8.39 ± 0.70 | 6.56 ± 0.71* | 6.09 ± 0.49* | 6.55 ± 0.50* | 7.06 ± 0.81* |
| miR-96 mimic group | 10 | 8.07 ± 0.37 | 4.38 ± 0.74*# | 4.23 ± 0.35*# | 4.27 ± 0.27*# | 5.54 ± 0.62*# |
| miR-96 inhibitor group | 10 | 8.11 ± 0.16 | 3.22 ± 0.71*# | 3.06 ± 0.44*# | 3.19 ± 0.32*# | 4.13 ± 0.59*# |
| CACNG5 group | 10 | 8.25 ± 0.21 | 3.56 ± 0.17*# | 3.41 ± 0.46*# | 3.37 ± 0.18*# | 4.15 ± 0.45*# |
| miR-96 mimic + CACNG5 group | 10 | 8.30 ± 0.69 | 6.36 ± 0.66* | 6.06 ± 0.73* | 6.60 ± 0.78* | 7.03 ± 0.67* |
Note: The test was repeated three times independently, and the one-way ANOVA analysis was used for comparison among multiple groups (n = 10)
PD Parkinson disease, NC Negative control, miR-96 microRNA-96, CACNG5 Calcium voltage-gated channel auxiliary subunit gamma 5, d Day
*P < 0.05 compared with the normal group, #, P < 0.05 compared with the PD group