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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Neurochem. 2018 Oct 31;147(4):526–540. doi: 10.1111/jnc.14588

Figure 3. CNO increases the firing rate and synaptic glutamate release of lamina II neurons expressing hM3D-mCherry.

Figure 3.

A. Representative recording traces show that bath application of 30 μM CNO depolarized and increased the firing frequency of lamina II neurons expressing hM3D-mCherry. Membrane potential is indicated on the left of individual recording traces. B. Quantification of the stimulatory effect of CNO on the firing rate of lamina II neurons expressing hM3D-mCherry (n = 15 neurons from 5 mice). C-E. Representative recording traces (C) and cumulative plots (D) and mean data with scattered plots (E) show the excitatory effect of 30 μM CNO on the frequency and amplitude of sEPSCs of lamina II neurons expressing hM3D-mCherry (n = 14 neurons from 4 mice). Data are expressed as mean ± S.E.M. * p < 0.05, ** p < 0.01 compared with the baseline control.