Figure 3.

Adjusted hazard ratios (HRs) of incident CHD per 2-fold increase in tibia lead concentration by combined dietary groups (n=594). Model was adjusted for age, BMI, total energy intake, smoking status (current/former/never), total cholesterol to HDL cholesterol ratio, education level and occupation. Low and high dietary groups were based on each dietary score cut at the median. Tests for effect modification were based on likelihood ratio tests comparing the full model (cross-product terms of Western diet×prudent diet, Western diet×tibia lead, prudent diet×tibia lead and a three-way interaction of Western diet×prudent diet×tibia lead) vs. the reduced model (the full model minus an interaction term of prudent diet×tibia lead or Western diet×tibia lead). P-for-interactions were 0.51 for prudent diet×tibia lead and prudent diet×Western diet×tibia lead; 0.07 for Western diet×tibia lead and prudent diet×Western diet×tibia lead.