Evaluation of the fluence intensity change in 1% Lipofundin at different depths. (A) The angle changed from 0 degree to 60 degrees, while the interval between the two output arms was fixed at 14 mm. (B) The interval ranged from 10 mm to 26 mm, while the angle was fixed at 35 degrees for the fluence evaluation. According to (A) and (B), the angles of the fiber bundle would not largely affect the fluence intensity, while a shorter interval (separation) of the two arms could greatly influence the intensity in scattering medium. Thus, we designed the interval of the two arms to be as short as possible for the system, while the angle was chosen as 35 degrees for experiments in both water and scattering medium.