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. 2018 Nov 21;18(11):4081. doi: 10.3390/s18114081

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Performance evaluation of the photoacoustic (PA) imaging system based on the PTI model. (A) The photos of the selected cortical blood vessel pre- and post-PTI within the cranial window. The yellow dashed line indicates the location of the PA B-scan image, while the black rectangle is the ischemic region. (B) Co-registered PA-US B-scan images. The cerebral blood volume (CBV) of the selected cerebral blood vessel shown in the post-PTI image was substantially lower than that shown in the pre-PTI image. (C) TTC staining results with and without PTI are presented to support the results of the in vivo PA image.