Table 1.

Demographics of cerebrospinal fluid donors

	CSF collection, aliquoting, and storage protocol used to evaluate effect of aliquot volume and tube type on Aβ1–42 recovery		Comparison of CSF collection, aliquoting, and storage protocols used to evaluate effect of GuHCl timing on Aβ recovery
	YNC	AD	YNC	DEM
No. of subjects	20	82	10	10
Age, years, mean (SD)	36 (5.9)	72 (8.4)	30 (10)	68 (6.3)
Male, n (%)	11 (55%)	33 (40%)	6 (60%)	5 (50%)
Female, n (%)	9 (45%)	49 (60%)	4 (40%)	5 (50%)
MMSE score (SD)	NA	21 (0.80)	NA	20 (2.2)

Abbreviations: Aβ Amyloid-β, AD Alzheimer’s disease, CSF Cerebrospinal fluid, DEM Dementia of unknown origin, GuHCl Guanidine hydrochloride, MMSE Mini Mental State Examination, YNC Young normal control subjects