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. 2011 May 27;16(6):4389–4400. doi: 10.3390/molecules16064389

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© 2011 by the authors;

licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Morphological observation of H22 cells by EM after treatment. The cells were examined under a transmission electronmicroscope (×5000 power, bar = 1 μm). A: normal hepatoma H22 cells; B: karyopyknosis, membrane integrity and formation of apoptotic bodies in high dosage CE-SB group.