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. 2011 Oct 11;16(10):8475–8503. doi: 10.3390/molecules16108475

Figure 1.

Figure 1

Inhibition of coxsackieviruses by WIN compounds. WIN compounds bind to the canyon pocket of CVB3 thereby inhibiting the binding of the virus to the cellular receptor CAR. WIN compounds also inhibit the uncoating and release of the viral RNA into the cytoplasm.