Table 5.

Cyclisation to 1,1-disubstituted 1,2,3,4-tetrahydroisoquinolines.

7	R1	R2	R3	Yield [%]	mp, °C
a	СОCH3	CH3	CH3	96	123–125
b	COC6H5	CH3	CH3	97	143–146
c	COCH2C6H5	CH3	CH3	97	oil
d	COOC2H5	CH3	CH3	90	55-56
e	SO2CH3	CH3	CH3	95	123–125
n	COC6H5	CH2C6H5	CH3	30	164–166
o	СОCH3	CH3	C2H5	60	76–81
p	COC6H5	CH3	C2H5	80	90–92
r	SO2CH3	CH3	C2H5	60	100–102
s	COC6H5	CH3	C6H5	60	103–133
t	SO2CH3	C6H5	C2H5	60	138–141