. 2011 Aug 3;16(8):6489–6501. doi: 10.3390/molecules16086489

Table 1.

Anti-influenza A (H2N2) virus activity of patchouli alcohol compared with oseltamivir.

Compound	CC₅₀ ^a (µM)	Influenza A (A/Udorn/307/72)
Compound	CC₅₀ ^a (µM)	IC₅₀^b (µM)	SI ^c
Patchouli alcohol	>20.0	4.03 ± 0.23 *	>4.96
Oseltamivir	>20.0	0.031 ± 0.012	>645.16

Values in this table represent the mean values (±SD) of three independent experiments (P < 0.01).

^a Cytotoxic effect was determined by MTT assay. CC₅₀ was the concentration that showed 50% cytotoxic effects in MDCK cells; ^b Antiviral activity was determined by MTT assay. IC₅₀ was the concentration that inhibited 50% of Influenza A [(Leningrad/134/17/1957) (H2N2)] virus replication in MDCK; ^c The selective index (SI) was calculated as CC₅₀/IC₅₀. The symbol * indicate a very significant difference p < 0.01 with respect to positive control (oseltamivir).