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. 2011 Aug 29;16(9):7344–7356. doi: 10.3390/molecules16097344

Table 1.

Km and IC50 values of the standard inhibitors reported in the literature.

Cytochrome/Substrate This study Reference
Km (µM) IC50 (µM) Km (µM) a IC50 (µM) a,b
3A4/BFC 48.94 0.045 50 0.06 ± 0.016 b
0.09 ± 0.03 a
2D6/AMMC 1.016 0.005 1.5 0.0069 ± 0.0006 b
0.5 ± 0.2 a
1A2/CEC 23.69 0.755 25 0.58 ± 0.05 b
1.4 ± 0.3 a
2C19/CEC 4.627 2.511 5 2 ± 0.5 b
3.2 ± 1.2 a

a Reference from database of Aurigene Discovery Technologies, Ltd.; b Donato et al. [13]. Data were expressed in standard error of the mean (S.E.M).