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. 2018 Nov 29;13(11):e0206478. doi: 10.1371/journal.pone.0206478

Table 2. CSF and routine laboratory analysis for the representative study group analyzed in the present study.

Standard value Study group
N Mean SD* CV* Median
Proteins [mg/L] 200–400 12 424.6 106.9 25.2% 413.5
White blood cell count [cells/mm3] 0–4 12 0.4 0.6 151.9% 0.0
Erythrocyte count [cells/mm3] 0–10 12 4.9 13.3 271.8% 0.0
CSF albumin [mg/L] 0.0–350.0 12 276.2 77.3 28.0% 255.5
Serum albumin [g/L] 35.00–55.00 12 42.7 2.6 6.1% 42.8
Albumin Quotient [ratio] < 8 12 6.5 1.8 27.4% 6.2
CSF IgG [mg/L] 10.0–40.0 12 29.4 8.0 27.4% 30.5
Serum IgG [g/L] 8.0–18.0 12 10.0 1.8 18.2% 9.7
IgG Quotient [ratio] ~ 2,3 12 3.0 0.9 29.4% 2.8
CSF IgA [mg/L] 1.5–6.0 12 5.3 2.9 55.3% 4.6
Serum IgA [g/L] 0.9–4.5 12 3.4 1.6 46.2% 3.1
IgA Quotient [ratio] ~ 1,3 12 1.5 0.6 39.9% 1.4
CSF IgM [mg/L] 0.0–1.0 12 0.2 0.1 37.5% 0.2
Serum IgM [g/L] 0.6–2.5 12 1.0 0.5 48.0% 0.8
IgM Quotient [ratio] ~ 0.3 12 0.3 0.3 82.7% 0.2

Clinical CSF parameters (e.g., red and white blood cell count and protein concentrations) were determined to ensure a healthy study group. In addition CSF/serum quotients were determined.

*SD = standard deviation, CV = coefficent of variation.