Skip to main content
. 2018 Nov 29;13(11):e0208198. doi: 10.1371/journal.pone.0208198

Fig 1. Clinical evaluation of effect of PAI on the ocular surface.

Fig 1

PAI solution diluted 6-, 8-, or 16-fold with saline and saline solution as a control were administered to rabbit eyes, followed by washing with saline 10 seconds later. Corneal epithelial damage was assessed by fluorescein staining. (A) Representative images of fluorescein corneal staining showed no substantial staining in the saline controls. (B) Representative images of fluorescein staining showed mild diffuse corneal staining at the central part of cornea in the 16-fold PAI-treated eyes with no obvious staining in the untreated controls, (C) mild diffuse fluorescein staining at the central part of cornea in all 8-fold PAI-treated eyes, and (D) patches and diffuse staining at the central part of cornea in 6-fold PAI-treated eyes.