Table 1. AD classification of fluorescein corneal staining (FL) and CR ratio (%) in rabbit eyes administered 4-, 6-, 8-, 16-fold diluted PAI solution, or saline as a control.

120 minutes after administration		AD classification of FL: Eyes	CR (%)
PAI solution	4-fold	• A2D2 : 6	65.8
	6-fold	• A2D2 : 3 • A1D1 : 3	71.2
	8-fold	• A1D1 : 6	77.4
	16-fold	• A1D1 : 5 • A0D0 : 1	83.6
Saline (control)		• A0D0 : 6	99.2