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. 2018 Nov 29;13(11):e0208198. doi: 10.1371/journal.pone.0208198

Table 2. AD classification of FL and CR ratio (%) in eyes administered 6- or 8-fold diluted PAI solution with/without wash-out by saline solution.

PAI 6-fold dilution PAI 8-fold dilution
Non-washed Washed Non-washed Washed
Hours after administration AD classification of FL: eyes CR (%) AD classification of FL: eyes CR (%) AD classification of FL: eyes CR (%) AD classification of FL: eyes CR (%)
0 • A0D0 : 6 100 • A0D0 : 6 100 • A0D0 : 6 100 • A0D0 : 6 100
24 • A1D1 : 4
• A1D2 : 1
• A2D1 : 1
67.2 • A1D1 : 5
• A2D2 : 1
88.1 • A0D0 : 1
• A1D1 : 3
• A2D2 : 2
65.9 • A0D0 : 5
A1D1 : 1
78.1
48 • A1D1 : 6 67.2 • A0D0 : 1
• A0D1 : 1
• A1D0 : 1
• A1D1 : 3
91.1 • A0D0 : 2
• A1D1 : 4
69.1 • A0D0 : 6 89.5
72 • A1D0 : 1
• A1D1 : 4
• A2D1 : 1
73.3 • A0D0 : 3
• A1D1 : 2
• A2D2 : 1
96.6 • A0D0 : 2
• A1D1 : 4
78.0 • A0D0 : 6 100
96 • A1D1 : 6 77.5 • A0D0 : 4
• A1D1 : 2
103.4 • A0D0 : 5
• A1D1 : 1
90.2 • A0D0 : 6 100

PAI: polyvinyl alcohol-iodine, FL: fluorescein staining, AD: area and density, CR: corneal resistance ratio (post-treatment/pre-treatment)